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Article

Coordinated conditional simulation with SLINK and SUP of many markers linked or associated to a trait in large pedigrees.

Human heredity - 1 Jan 2011

Schäffer Alejandro A, Lemire Mathieu, Ott Jürg, Lathrop G Mark, Weeks Daniel E

Abstract excerpt

Simulation of genotypes in pedigrees is an important tool to evaluate the power of a linkage or an association study and to assess the empirical significance of results. SLINK is a widely-used package for pedigree simulations, but its implementation has not previously been described in a published paper. SLINK was initially derived from the LINKAGE programs. Over the 20 years since its release, SLINK has been...

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PMID: 21734403
DOI: 10.1159/000324177
PMCID: PMC3136384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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