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Article

The effect of linkage disequilibrium on linkage analysis of incomplete pedigrees.

BMC genetics - 30 Dec 2005

Levinson Douglas F, Holmans Peter

Abstract excerpt

Dense SNP maps can be highly informative for linkage studies. But when parental genotypes are missing, multipoint linkage scores can be inflated in regions with substantial marker-marker linkage disequilibrium (LD). Such regions were observed in the Affymetrix SNP genotypes for the Genetic Analysis Workshop 14 (GAW14) Collaborative Study on the Genetics of Alcoholism (COGA) dataset, providing an opportunity to...

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Identifiers

PMID: 16451672
DOI: 10.1186/1471-2156-6-S1-S6
PMCID: PMC1866723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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