Article
Pedigree generation for analysis of genetic linkage and association.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2004
Bass M P, Martin E R, Hauser E R
Abstract excerpt
We have developed a software package, SIMLA (simulation of linkage and association), which can be used to generate pedigree data under user-specified conditions. The number and location of disease loci, disease penetrances, marker locations, and marker disequilibrium with a disease locus and with other markers can be controlled. In addition, the pedigree size and availability of genotype data may also be...
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