Article
A system for exact and approximate genetic linkage analysis of SNP data in large pedigrees.
Bioinformatics (Oxford, England) - 15 Jan 2013
Silberstein Mark, Weissbrod Omer, Otten Lars, Tzemach Anna, Anisenia Andrei, Shtark Oren, Tuberg Dvir, Galfrin Eddie, Gannon Irena, Shalata Adel, Borochowitz Zvi U, Dechter Rina, Thompson Elizabeth, Geiger Dan
Abstract excerpt
MOTIVATION: The use of dense single nucleotide polymorphism (SNP) data in genetic linkage analysis of large pedigrees is impeded by significant technical, methodological and computational challenges. Here we describe Superlink-Online SNP, a new powerful online system that streamlines the linkage analysis of SNP data. It features a fully integrated flexible processing workflow comprising both well-known and novel...
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