Article
Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics.
American journal of human genetics - 1 Jun 1996
Sobel E, Lange K
Abstract excerpt
The introduction of stochastic methods in pedigree analysis has enabled geneticists to tackle computations intractable by standard deterministic methods. Until now these stochastic techniques have worked by running a Markov chain on the set of genetic descent states of a pedigree. Each descent state specifies the paths of gene flow in the pedigree and the founder alleles dropped down each path. The current paper...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
