Article
CYP1A2 genotype and rheumatoid arthritis in Koreans.
Rheumatology international - 1 Aug 2010
Cornelis Marilyn C, Bae Sang-Cheol, Kim Il, El-Sohemy Ahmed
Abstract excerpt
Cytochrome P540 (CYP) 1A2 plays a role in the production of reactive oxygen species (ROS), which have been implicated in the development of rheumatoid arthritis (RA). The objective of this study was to investigate the association between a common polymorphism in the CYP1A2 gene with risk and severity of RA in a Korean population. Cases (n = 1321) with RA and controls (n = 1037) were genotyped for the CYP1A2 -163...
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