Article
HLA-G +3142 polymorphism as a susceptibility marker in two rheumatoid arthritis populations in Brazil.
Tissue antigens - 1 Apr 2014
Veit T D, de Lima C P S, Cavalheiro L C, Callegari-Jacques S M, Brenol C V, Brenol J C T, Xavier R M, da Cunha Sauma M F L, dos Santos E J M, Chies J A B
Abstract excerpt
In this study, we sought to investigate the genetic influence of two HLA-G 3'-untranslated region (3'-UTR) polymorphisms - 14 bp (rs66554220) and +3142C>G (rs1063320) and their compounding haplotypes in susceptibility to rheumatoid arthritis (RA) in a two-region Brazilian study comprising of 539 patients and 489 controls. All subjects were polymerase chain reaction (PCR) genotyped for the referred polymorphisms...
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