Article
Cyclooxygenase-2 genotype and rheumatoid arthritis.
The Journal of rheumatology - 1 Jul 2006
Lee Kyu Hoon, Kim Hee-Sang, El-Sohemy Ahmed, Cornelis Marilyn C, Uhm Wan-Sik, Bae Sang-Cheol
Abstract excerpt
OBJECTIVE: To determine the association between cyclooxygenase-2 (COX-2) genotypes and risk and severity of rheumatoid arthritis (RA) in a Korean population. METHODS: A total of 258 Korean patients with RA and 400 control subjects were recruited from Hanyang University Hospital. Subjects were genotyped for the -765G/C polymorphism of the COX-2 gene by RFLP-PCR analysis. Odds ratios (OR) and 95% confidence...
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