Article
Association between the polymorphisms of glutathione S-transferase genes and rheumatoid arthritis: a meta-analysis.
Gene - 25 May 2013
Ji Jong Dae, Lee Won Jin
Abstract excerpt
The glutathione S-transferases (GSTs) are a family of phase II xenobiotic metabolizing enzymes known to be involved in the detoxification and elimination of reactive oxygen species (ROS), thus defending tissues against oxidative stress. Recently, several studies have examined the potential contributions of GSTM1 and GSTT1 gene polymorphisms toward susceptibility to rheumatoid arthritis (RA), but these studies...
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