Increased susceptibility to rheumatoid arthritis in Koreans heterozygous for HLA-DRB1*0405 and *0901.

doi:10.1002/art.20608

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Article

Increased susceptibility to rheumatoid arthritis in Koreans heterozygous for HLA-DRB10405 and 0901.

Arthritis and rheumatism - 1 Nov 2004

Lee Hye-Soon, Lee Kyung Wha, Song Gwan Gyu, Kim Hyun-Ah, Kim Shin-Yoon, Bae Sang-Cheol

Abstract excerpt

OBJECTIVE: To investigate the association of susceptibility and protective HLA-DRB1 alleles with rheumatoid arthritis (RA) and its clinical markers in an Asian population. METHODS: All RA patients (n = 574) and control subjects (n = 392) were Korean. HLA-DRB1 typing and further subtyping of all alleles was performed by polymerase chain reaction, sequence-specific oligonucleotide probe hybridization, and direct...

Topics

Adult
Alleles
Arthritis, Rheumatoid
Asian People
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
HLA-DR Antigens
HLA-DRB1 Chains
Heterozygote
Humans
Male
Middle Aged

Source

Open in PubMed

Identifiers

PMID: 15529363
DOI: 10.1002/art.20608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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