Article
Increased susceptibility to rheumatoid arthritis in Koreans heterozygous for HLA-DRB1*0405 and *0901.
Arthritis and rheumatism - 1 Nov 2004
Lee Hye-Soon, Lee Kyung Wha, Song Gwan Gyu, Kim Hyun-Ah, Kim Shin-Yoon, Bae Sang-Cheol
Abstract excerpt
OBJECTIVE: To investigate the association of susceptibility and protective HLA-DRB1 alleles with rheumatoid arthritis (RA) and its clinical markers in an Asian population. METHODS: All RA patients (n = 574) and control subjects (n = 392) were Korean. HLA-DRB1 typing and further subtyping of all alleles was performed by polymerase chain reaction, sequence-specific oligonucleotide probe hybridization, and direct...
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