Article
Glutathione S-transferase M1, T1, and P1 genotypes and rheumatoid arthritis.
The Journal of rheumatology - 1 Jun 2005
Yun Bo Ra, El-Sohemy Ahmed, Cornelis Marilyn C, Bae Sang-Cheol
Abstract excerpt
OBJECTIVE: To determine the effects of genetic polymorphisms of glutathione S-transferase (GST) M1, GSTT1, and GSTP on risk and severity of rheumatoid arthritis (RA) in a Korean population. METHODS: A total of 258 patients with RA and 400 disease-free controls were enrolled. GST genotypes were determined by RFLP-PCR. HLA-DRB 1 typing and further subtyping of all alleles was performed using sequence-specific...
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