Article
Chromosomally and microsatellite stable colorectal carcinomas without the CpG island methylator phenotype in a molecular classification.
International journal of oncology - 1 Aug 2009
Ostwald Christiane, Linnebacher Michael, Weirich Volker, Prall Friedrich
Abstract excerpt
We hypothesized that in a comprehensive analysis of colorectal carcinomas (CRC) the three currently known major molecular mechanisms of carcinogenesis (i.e., chromosomal instability, microsatellite instability, and CpG island methylator phenotype, CIMP) would associate with the molecular features indicative of these pathways, allowing a molecular classification. A prospectively collected clinicopathologically...
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