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Article

Molecular pathological classification of colorectal cancer.

Virchows Archiv : an international journal of pathology - 1 Aug 2016

Müller Mike F, Ibrahim Ashraf E K, Arends Mark J

Abstract excerpt

Colorectal cancer (CRC) shows variable underlying molecular changes with two major mechanisms of genetic instability: chromosomal instability and microsatellite instability. This review aims to delineate the different pathways of colorectal carcinogenesis and provide an overview of the most recent advances in molecular pathological classification systems for colorectal cancer. Two molecular pathological...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27325016
DOI: 10.1007/s00428-016-1956-3
PMCID: PMC4978761

Genes

APC
KRAS
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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