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Article

Vps-C complexes: gatekeepers of endolysosomal traffic.

Current opinion in cell biology - 1 Aug 2009

Nickerson Daniel P, Brett Christopher L, Merz Alexey J

Abstract excerpt

Genetic studies in yeast, plants, insects, and mammals have identified four universally conserved proteins, together called Vps Class C, that are essential for late endosome and lysosome assembly and for numerous endolysosomal trafficking pathways, including the terminal stages of autophagy. Two Vps-C complexes, HOPS and CORVET, incorporate diverse biochemical functions: they tether membranes, stimulate Rab...

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Identifiers

PMID: 19577915
DOI: 10.1016/j.ceb.2009.05.007
PMCID: PMC2807627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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