Article
A perspective from transport protein particle: vesicle tether and human diseases.
Sheng li xue bao : [Acta physiologica Sinica] - 25 Feb 2014
Li Chunman, Yu Sidney
Abstract excerpt
Vesicle-mediated transport of proteins is a highly regulated, multi-step process. When the vesicle is approaching its target membrane compartment, many factors are required to provide specificity and tethering between the incoming vesicle and the target membrane, before vesicle fusion can occur. Tethering factors, which include multisubunit complexes, coiled-coil proteins, with the help of small GTPases, provide...
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