Article
A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae.
Molecular & cellular proteomics : MCP - 1 Jun 2011
Dokudovskaya Svetlana, Waharte Francois, Schlessinger Avner, Pieper Ursula, Devos Damien P, Cristea Ileana M, Williams Rosemary, Salamero Jean, Chait Brian T, Sali Andrej, Field Mark C, Rout Michael P, Dargemont Catherine
Abstract excerpt
The presence of multiple membrane-bound intracellular compartments is a major feature of eukaryotic cells. Many of the proteins required for formation and maintenance of these compartments share an evolutionary history. Here, we identify the SEA (Seh1-associated) protein complex in yeast that contains the nucleoporin Seh1 and Sec13, the latter subunit of both the nuclear pore complex and the COPII coating...
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