Article
High-throughput minor histocompatibility antigen prediction.
Bioinformatics (Oxford, England) - 15 Sept 2009
DeLuca David S, Eiz-Vesper Britta, Ladas Nektarios, Khattab Barbara Anna-Maria, Blasczyk Rainer
Abstract excerpt
MOTIVATION: Minor histocompatibility antigens (mHags) are a diverse collection of MHC-bound peptides that have immunological implications in the context of allogeneic transplantation because of their differential presence in donor and host, and thus play a critical role in the induction of the detrimental graft-versus-host disease (GvHD) or in the development of the beneficial graft-versus-leukemia (GvL) effect....
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