Article
Leukemia-associated minor histocompatibility antigen discovery using T-cell clones isolated by in vitro stimulation of naive CD8+ T cells.
Blood - 10 Jun 2010
Bleakley Marie, Otterud Brith E, Richardt Julia L, Mollerup Audrey D, Hudecek Michael, Nishida Tetsuya, Chaney Colette N, Warren Edus H, Leppert Mark F, Riddell Stanley R
Abstract excerpt
T-cell immunotherapy that targets minor histocompatibility (H) antigens presented selectively by recipient hematopoietic cells, including leukemia, could prevent and treat leukemic relapse after hematopoietic cell transplantation without causing graft-versus-host disease. To provide immunotherapy...
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