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Article

A Model of Minor Histocompatibility Antigens in Allogeneic Hematopoietic Cell Transplantation.

Frontiers in immunology - 1 Jan 2021

Martin Paul J, Levine David M, Storer Barry E, Zheng Xiuwen, Jain Deepti, Heavner Ben, Norris Brandon M, Geraghty Daniel E, Spellman Stephen R, Sather Cassie L, Wu Feinan, Hansen John A

Abstract excerpt

Minor histocompatibility antigens (mHAg) composed of peptides presented by HLA molecules can cause immune responses involved in graft-versus-host disease (GVHD) and graft-versus-leukemia effects after allogeneic hematopoietic cell transplantation (HCT). The current study was designed to identify individual graft-versus-host genomic mismatches associated with altered risks of acute or chronic GVHD or relapse after...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34868058
DOI: 10.3389/fimmu.2021.782152
PMCID: PMC8636906

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