Article
Investigation of the SPINK1 N34S mutation in Romanian patients with alcoholic chronic pancreatitis. A clinical analysis based on the criteria of the M-ANNHEIM classification.
Journal of gastrointestinal and liver diseases : JGLD - 1 Jun 2009
Diaconu Brindusa L, Ciobanu Lidia, Mocan Teodora, Pfützer Roland H, Scafaru Marius P, Acalovschi Monica, Singer Manfred V, Schneider Alexander
Abstract excerpt
BACKGROUND AND AIMS: The N34S mutation in the serine protease inhibitor Kazal type I (SPINK1) gene has been associated with chronic pancreatitis. Clinical data about the phenotypic expression of alcoholic chronic pancreatitis with the N34S variant are limited. The prevalence of the N34S mutation in patients with chronic pancreatitis and healthy individuals from Eastern Europe is unknown. METHODS: We studied...
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