Differential roles of the SPINK1 gene mutations in alcoholic and nonalcoholic chronic pancreatitis.

Abstract excerpt

BACKGROUND: Risk factors for chronic pancreatitis (CP) are largely unknown except for alcohol. Identification of environmental and genetic risk factors is important for the early diagnosis of CP. We here examined the prevalence of the serine protease inhibitor Kazal type 1 (SPINK1) gene mutations in Japanese patients with CP, and whether the disease course was different between mutation-positive and -negative...

Topics

Join the communities discussing this publication.

• Carrier Proteins
• Case-Control Studies
• Pancreatic Neoplasms
• Pancreatitis, Alcoholic
• Pancreatitis, Chronic