Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease.

Neuroscience letters - 2 Oct 2009

Solomon Alina, Leoni Valerio, Kivipelto Miia, Besga Ariadna, Oksengård Anne Rita, Julin Per, Svensson Leif, Wahlund Lars-Olof, Andreasen Niels, Winblad Bengt, Soininen Hilkka, Björkhem Ingemar

Abstract excerpt

OBJECTIVES: Cholesterol has been linked to Alzheimer's disease (AD) and plasma 24S-hydroxycholesterol (24OHC) has been suggested as a surrogate marker for brain cholesterol metabolism. This study investigates the relation of 24OHC as well as markers of extracerebral cholesterol homeostasis (lanosterol, lathosterol, cholesterol, LDL-C, HDL-C and 27-hydroxycholesterol) with brain volumes in memory clinic patients....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Cholesterol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, HDL

Share to Cholesterol, LDL

Share to Cognition Disorders

Share to Hydroxycholesterols

Share to Organ Size

Share to Sex Factors

Source

Identifiers

PMID: 19560513
DOI: 10.1016/j.neulet.2009.06.073

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease.PMID 19560513Read ↗

Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients.Semantic proximity Read ↗

Alterations of cholesterol precursor levels in Alzheimer's disease.Semantic proximity Read ↗

Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study.Semantic proximity Read ↗

Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls.Semantic proximity Read ↗

Altered Circulating Free Oxysterols in Mild Cognitive Impairment: Relationship to Diet, Lipids and GeneticsSemantic proximity Read ↗

Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.Semantic proximity Read ↗

Long-term statin therapy and CSF cholesterol levels: implications for Alzheimer's disease.Semantic proximity Read ↗

A CYP46 T/C SNP modulates parahippocampal and hippocampal morphology in young subjects.Semantic proximity Read ↗

Statins have therapeutic potential for the treatment of Alzheimer's disease, likely via protection of the neurovascular unit in the AD brain.Semantic proximity Read ↗

The impairment of cholesterol metabolism in Huntington disease.Semantic proximity Read ↗

Brain MRI, apoliprotein E genotype, and plasma homocysteine in American Indian Alzheimer disease patients and Indian controls.Semantic proximity Read ↗

Medial temporal lobe atrophy, apolipoprotein genotype, and plasma homocysteine in Sri Lankan patients with Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.