Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.

Neuroreport - 26 Jun 2000

Papassotiropoulos A, Lütjohann D, Bagli M, Locatelli S, Jessen F, Rao M L, Maier W, Björkhem I, von Bergmann K, Heun R

Abstract excerpt

The conversion of brain cholesterol into 24S-hydroxycholesterol and its subsequent release into the periphery is probably an important step for the maintenance of brain cholesterol homeostasis. Recent findings suggest that plasma 24S-hydroxycholesterol may be elevated in Alzheimer's disease (AD) and vascular dementia at least at some stage of the disease, suggesting increased brain cholesterol turnover during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Biomarkers

Share to Genotype

Share to Hydroxycholesterols

Share to Nerve Degeneration

Share to Severity of Illness Index

Source

Identifiers

PMID: 10884051
DOI: 10.1097/00001756-200006260-00030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.PMID 10884051Read ↗

Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients.Semantic proximity Read ↗

Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls.Semantic proximity Read ↗

Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study.Semantic proximity Read ↗

Lipid metabolism in cognitive decline and dementia.Semantic proximity Read ↗

Influence of APOE4 genotype on PCSK9-lipids association in cerebrospinal fluid and serum of patients in the Alzheimer's disease continuum.Semantic proximity Read ↗

Alterations of cholesterol precursor levels in Alzheimer's disease.Semantic proximity Read ↗

Cholesterol metabolism and homeostasis in the brainSemantic proximity Read ↗

SREBP-1a polymorphism influences the risk of Alzheimer's disease in carriers of the ApoE4 allele.Semantic proximity Read ↗

24S-Hydroxycholesterol: A potential brain-derived biomarker of Huntington’s DiseaseSemantic proximity Read ↗

Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease.Semantic proximity Read ↗

Altered Circulating Free Oxysterols in Mild Cognitive Impairment: Relationship to Diet, Lipids and GeneticsSemantic proximity Read ↗

Serum lipoprotein profile and APOE genotype in Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.