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Article

A CYP46 T/C SNP modulates parahippocampal and hippocampal morphology in young subjects.

Neurobiology of aging - 1 Jun 2011

Hänggi Jürgen, Mondadori Christian R A, Buchmann Andreas, Henke Katharina, Hock Christoph

Abstract excerpt

There is evidence that brain cholesterol metabolism modulates the vulnerability for Alzheimer's disease (AD). Previous data showed that brain β-amyloid load in elderly subjects with the CYP46 (cholesterol 24S-hydroxylase) TT-positive genotype was higher than in CYP46 TT-negative elderly subjects....

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PMID: 19647891
DOI: 10.1016/j.neurobiolaging.2009.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19647891-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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