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Article

Alterations of cholesterol precursor levels in Alzheimer's disease.

Biochimica et biophysica acta - 1 Aug 2010

Kölsch Heike, Heun Reinhard, Jessen Frank, Popp Julius, Hentschel Frank, Maier Wolfgang, Lütjohann Dieter

Abstract excerpt

Cerebral and extracerebral cholesterol metabolism are altered in Alzheimer's disease (AD) as indicated by reduced plasma levels of the cholesterol elimination products 24S-hydroxycholesterol, which is of cerebral origin, and of 27-hydroxycholesterol, which is formed extracerebrally. However, it has to be evaluated, if changes of cholesterol metabolism in the whole body or in the CNS are exclusively due to the...

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Identifiers

PMID: 20226877
DOI: 10.1016/j.bbalip.2010.03.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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