Article
Single-marker and two-marker association tests for unphased case-control genotype data, with a power comparison.
Genetic epidemiology - 1 Jan 2010
Kim Sulgi, Morris Nathan J, Won Sungho, Elston Robert C
Abstract excerpt
In case-control single nucleotide polymorphism (SNP) data, the allele frequency, Hardy Weinberg Disequilibrium, and linkage disequilibrium (LD) contrast tests are three distinct sources of information about genetic association. While all three tests are typically developed in a retrospective context, we show that prospective logistic regression models may be developed that correspond conceptually to the...
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