Article
Joint analysis of tightly linked SNPs in screening step of genome-wide association studies leads to increased power.
European journal of human genetics : EJHG - 1 Aug 2009
Becker Tim, Herold Christine
Abstract excerpt
Recent developments in genome-wide association studies (GWAS) have lead to the localization of disease genes for many complex diseases. The scrutiny of the respective publications reveals, first, that statistical analysis is restricted typically to single-marker analysis in the first step, and that, second, the presence of multiple, independently associated SNPs within the same linkage disequilibrium (LD) region...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
