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Article

Involvement of phospholipase C-related inactive protein in the mouse reproductive system through the regulation of gonadotropin levels.

Biology of reproduction - 1 Oct 2009

Matsuda Miho, Tsutsumi Koushirou, Kanematsu Takashi, Fukami Kiyoko, Terada Yoshihiro, Takenawa Tadaomi, Nakayama Keiichi I, Hirata Masato

Abstract excerpt

Phospholipase C-related but catalytically inactive protein (comprising PRIP-1 and PRIP-2 [officially designated PLCL1 and PLCL2]) was first identified in our laboratory, but the biological functions have remained elusive. Therefore, we generated Plcl1 and Plcl2 double-knockout mice (Plcl1(tm1Mh); Plcl2(tm1Tta)) to gain insight into the biological function. Double-knockout mice apparently grew normally and became...

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Source

Identifiers

PMID: 19553601
DOI: 10.1095/biolreprod.109.076760

Genes

PLCL1
PLCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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