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Article

The Mutation of the Ap3b1 Gene Causes Uterine Hypoplasia in Pearl Mice.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Jan 2020

Jing Renwei, Kong Yu, Han Gang, Zhang Jingye, Li Kailin, Dong Xuan, Yan Jie, Zhang Haiqing, Han Jia, Feng Lijun

Abstract excerpt

The pearl (pe) mouse mutant has been identified as a model for Hermansky-Pudlak syndrome and bears a mutation in the beta3A subunit of the AP-3 complex, which has a core function in the biogenesis and function of various lysosomal-related organelles. Through large-scale mating, we found that female pearl mice also displayed reduced fertility with a smaller litter size. Abnormal uteri in both 1-month-old and...

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Identifiers

PMID: 32016796
DOI: 10.1007/s43032-019-00006-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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