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Article

Carboxypeptidase E in the mouse placenta.

Differentiation; research in biological diversity - 1 Dec 2006

Singh Umashankar, Yu Yang, Kalinina Elena, Konno Toshihiro, Sun Tong, Ohta Hiroshi, Wakayama Teruhiko, Soares Michael J, Hemberger Myriam, Fundele Reinald H

Abstract excerpt

Carboxypeptidase E (CPE) has important functions in processing of endocrine pro-peptides, such as pro-insulin, pro-opiomelanocortin, or pro-gonadotropin-releasing hormone, as evidenced by the hyper-pro-insulinemia, obesity, and sterility of Cpe mutant mice. Down-regulation of Cpe in enlarged placentas of interspecific hybrid (interspecies hybrid placental dysplasia (IHPD)) and cloned mice suggested that reduced...

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Source

Identifiers

PMID: 17177860
DOI: 10.1111/j.1432-0436.2006.00093.x

Genes

CPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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