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Luteinizing hormone receptor knockout mouse: What has it taught us?

22 Jan 2025

Abstract excerpt

Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis in Leydig cells and in the ovary in theca, luteal, and luteinizing...

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PMID: 39840520
DOI: 10.1111/andr.70000

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