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Article

The biological significance of phospholipase C beta 1 gene mutation in mouse sperm in the acrosome reaction, fertilization, and embryo development.

Journal of assisted reproduction and genetics - 1 May 2001

Choi D, Lee E, Hwang S, Jun K, Kim D, Yoon B K, Shin H S, Lee J H

Abstract excerpt

PURPOSE: We carried out this study to evaluate the biological significance of phospholipase C beta 1 gene mutation in mouse sperm in the acrosome reaction, fertilization, and embryo development. METHODS: Study subjects were divided into two groups according to the sperm [intact phospholipase C (PLC) beta 1 and PLC beta 1-/- C57BL/6J x CBA F1 mouse sperm] used. The positive acrosome reaction rate labeled with...

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Share to Embryo, Mammalian
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infertility, Male

Share to Mice, Inbred CBA

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Share to Phospholipase C beta

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Share to Type C Phospholipases

Source

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Identifiers

PMID: 11464583
DOI: 10.1023/a:1016622519228
PMCID: PMC3455337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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