Article
Involvement of Nlrp9a/b/c in mouse preimplantation development.
Reproduction (Cambridge, England) - 1 Aug 2020
Kanzaki Satoko, Tamura Shiori, Ito Toshiaki, Wakabayashi Mizuki, Saito Koji, Kato Shigeki, Ohta Yasutaka, Sekita Yoichi, Kimura Tohru
Abstract excerpt
Nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain-containing proteins (NRLPs) are central components of the inflammasome. Accumulating evidence has shown that a reproductive clade of NRLPs is predominantly expressed in oocyte to cleavage stage embryos and participates in mammalian preimplantation development as a component of a multiprotein complex known as the subcortical maternal...
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