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Article

Mechanism for HIV-1 Tat insertion into the endosome membrane.

The Journal of biological chemistry - 21 Aug 2009

Yezid Hocine, Konate Karidia, Debaisieux Solène, Bonhoure Anne, Beaumelle Bruno

Abstract excerpt

The human immunodeficiency virus, type 1, transactivating protein Tat is a small protein that is strictly required for viral transcription and multiplication within infected cells. The infected cells actively secrete Tat using an unconventional secretion pathway. Extracellular Tat can affect different cell types and induce severe cell dysfunctions ranging from cell activation to cell death. To elicit most cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to tat Gene Products, Human Immunodeficiency Virus

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Identifiers

PMID: 19549783
DOI: 10.1074/jbc.M109.023705
PMCID: PMC2755682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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