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Article

Gp41 dynamically interacts with the TCR in the immune synapse and promotes early T cell activation.

Scientific reports - 27 Jun 2018

Yakovian Oren, Schwarzer Roland, Sajman Julia, Neve-Oz Yair, Razvag Yair, Herrmann Andreas, Sherman Eilon

Abstract excerpt

The HIV-1 glycoprotein gp41 critically mediates CD4+ T-cell infection by HIV-1 during viral entry, assembly, and release. Although multiple immune-regulatory activities of gp41 have been reported, the underlying mechanisms of these activities remain poorly understood. Here we employed multi-colour single molecule localization microscopy (SMLM) to resolve interactions of gp41 proteins with cellular proteins at the...

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Identifiers

PMID: 29950577
DOI: 10.1038/s41598-018-28114-5
PMCID: PMC6021400

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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