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Article

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth.

Molecular psychiatry - 1 Feb 2010

Ghiani C A, Starcevic M, Rodriguez-Fernandez I A, Nazarian R, Cheli V T, Chan L N, Malvar J S, de Vellis J, Sabatti C, Dell'Angelica E C

Abstract excerpt

Previous studies have implicated DTNBP1 as a schizophrenia susceptibility gene and its encoded protein, dysbindin, as a potential regulator of synaptic vesicle physiology. In this study, we found that endogenous levels of the dysbindin protein in the mouse brain are developmentally regulated, with higher levels observed during embryonic and early postnatal ages than in young adulthood. We obtained biochemical...

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Identifiers

PMID: 19546860
DOI: 10.1038/mp.2009.58
PMCID: PMC2811213

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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