Article
The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis.
Science (New York, N.Y.) - 20 Nov 2009
Dickman Dion K, Davis Graeme W
Abstract excerpt
The molecular mechanisms that achieve homeostatic stabilization of neural function remain largely unknown. To better understand how neural function is stabilized during development and throughout life, we used an electrophysiology-based forward genetic screen and assessed the function of more than 250 neuronally expressed genes for a role in the homeostatic modulation of synaptic transmission in Drosophila. This...
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