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Article

Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor.

Human molecular genetics - 1 Oct 2015

Gokhale Avanti, Vrailas-Mortimer Alysia, Larimore Jennifer, Comstra Heather S, Zlatic Stephanie A, Werner Erica, Manvich Daniel F, Iuvone P Michael, Weinshenker David, Faundez Victor

Abstract excerpt

Environmental factors and susceptible genomes interact to determine the risk of neurodevelopmental disorders. Although few genes and environmental factors have been linked, the intervening cellular and molecular mechanisms connecting a disorder susceptibility gene with environmental factors remain mostly unexplored. Here we focus on the schizophrenia susceptibility gene DTNBP1 and its product dysbindin, a subunit...

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Identifiers

PMID: 26199316
DOI: 10.1093/hmg/ddv282
PMCID: PMC4572075

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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