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Article

Accounting for linkage disequilibrium in association analysis of diverse populations.

Genetic epidemiology - 1 Apr 2014

Charles Bashira A, Shriner Daniel, Rotimi Charles N

Abstract excerpt

The National Human Genome Research Institute's catalog of published genome-wide association studies (GWAS) lists over 10,000 genetic variants collectively associated with over 800 human diseases or traits. Most of these GWAS have been conducted in European-ancestry populations. Findings gleaned from these studies have led to identification of disease-associated loci and biologic pathways involved in disease...

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PMID: 24464495
DOI: 10.1002/gepi.21788

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