Article
varLD: a program for quantifying variation in linkage disequilibrium patterns between populations.
Bioinformatics (Oxford, England) - 1 May 2010
Ong Rick Twee-Hee, Teo Yik-Ying
Abstract excerpt
MOTIVATION: Linkage disequilibrium (LD) differences between populations can potentially result in failure to replicate primary signals of trait association in independent genome-wide association studies (GWAS). However, such inter-population LD differences can be leveraged to narrow the search for common causal variants responsible for the association signals observed. The ability to assess and quantify LD...
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