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Article

A thymic stromal lymphopoietin gene variant is associated with asthma and airway hyperresponsiveness.

The Journal of allergy and clinical immunology - 1 Aug 2009

He Jian-Qing, Hallstrand Teal S, Knight Darryl, Chan-Yeung Moira, Sandford Andrew, Tripp Ben, Zamar David, Bossé Yohan, Kozyrskyj Anita L, James Alan, Laprise Catherine, Daley Denise

Abstract excerpt

BACKGROUND: The epithelial cell-derived protein thymic stromal lymphopoietin stimulates dendritic and mast cells to promote proallergic T(H)2 responses. Studies of transgenic expression of thymic stromal lymphopoietin and its receptor knockout mice have emphasized its critical role in the development of allergic inflammation. Association of genetic variation in thymic stromal lymphopoietin with IgE levels has...

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Identifiers

PMID: 19539984
DOI: 10.1016/j.jaci.2009.04.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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