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Article

TSLP disease-associated genetic variants combined with airway TSLP expression influence asthma risk.

The Journal of allergy and clinical immunology - 1 Jan 2022

Murrison Liza Bronner, Ren Xiaomeng, Preusse Kristina, He Hua, Kroner John, Chen Xiaoting, Jenkins Seth, Johansson Elisabet, Biagini Jocelyn M, Weirauch Matthew T, Kopan Raphael, Martin Lisa J, Khurana Hershey Gurjit K

Abstract excerpt

BACKGROUND: Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine important in initiation of allergic inflammation. Single nucleotide polymorphisms (SNPs) in TSLP are associated with asthma, yet studies have shown inconsistent associations between circulating TSLP and asthma. Studies that integrate the combined effects of TSLP genotype, TSLP mRNA, circulating TSLP levels, and asthma outcome are...

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Source

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Identifiers

PMID: 34111451
DOI: 10.1016/j.jaci.2021.05.033
PMCID: PMC9119142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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