Article
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis.
The Journal of allergy and clinical immunology - 1 Jul 2010
Sherrill Joseph D, Gao Pei-Song, Stucke Emily M, Blanchard Carine, Collins Margaret H, Putnam Phil E, Franciosi James P, Kushner Jonathan P, Abonia J Pablo, Assa'ad Amal H, Kovacic Melinda Butsch, Biagini Myers Jocelyn M, Bochner Bruce S, He Hua, Hershey Gurjit Khurana, Martin Lisa J, Rothenberg Marc E
Abstract excerpt
BACKGROUND: The genetic cause of eosinophilic esophagitis (EE) has been largely unexplored until a recent genome-wide association study identified a disease susceptibility locus on 5q22, a region that harbors the thymic stromal lymphopoietin (TSLP) gene. However, it is unclear whether the observe...
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