Article
Thymic stromal lymphopoietin: a central regulator of allergic asthma
14 Jun 2014
Abstract excerpt
INTRODUCTION: Epithelial cell-derived mediators have emerged as key players for instigating local remodeling and the associated cellular inflammation in asthmatic airways. In particular, the epithelial-derived cytokine, thymic stromal lymphopoietin (TSLP), has been identified as a master switch for allergic inflammation. AREAS COVERED: TSLP is expressed by structural and immune cells at the site of allergen entry...
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