Article
TSLP polymorphisms are associated with asthma in a sex-specific fashion.
Allergy - 1 Dec 2010
Hunninghake G M, Soto-Quirós M E, Avila L, Kim H P, Lasky-Su J, Rafaels N, Ruczinski I, Beaty T H, Mathias R A, Barnes K C, Wilk J B, O'Connor G T, Gauderman W James, Vora H, Baurley J W, Gilliland F, Liang C, Sylvia J S, Klanderman B J, Sharma S S, Himes B E, Bossley C J, Israel E, Raby B A, Bush A, Choi A M, Weiss S T, Celedón J C
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in thymic stromal lymphopoietin (TSLP) have been associated with IgE (in girls) and asthma (in general). We sought to determine whether TSLP SNPs are associated with asthma in a sex-specific fashion. METHODS: We conducted regular and sex-stratified analyses of association between SNPs in TSLP and asthma in families of children with asthma in Costa Rica....
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