Article
The bcl2 -938CC genotype has poor prognosis and lower survival in renal cancer.
The Journal of urology - 1 Aug 2009
Hirata Hiroshi, Hinoda Yuji, Nakajima Koichi, Kikuno Nobuyuki, Suehiro Yutaka, Tabatabai Z Laura, Ishii Nobuhisa, Dahiya Rajvir
Abstract excerpt
PURPOSE: A single nucleotide polymorphism (-938C/A, rs2279115) was found in the bcl2 gene, whose -938A allele is significantly associated with increased Bcl2 expression compared with that of the C allele. Bcl2 up-regulation was reported to be associated with longer survival in patients with renal cancer. However, to our knowledge there is currently no information on the role of the bcl2-938C/A single nucleotide...
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