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Article

Association of the AA genotype of the BCL2 (-938C>A) promoter polymorphism with better survival in ovarian cancer.

The International journal of biological markers - 1 Jan 2000

Heubner Martin, Wimberger Pauline, Otterbach Friedrich, Kasimir-Bauer Sabine, Siffert Winfried, Kimmig Rainer, Nückel Holger

Abstract excerpt

BACKGROUND: Bcl-2 plays a key role in the regulation of apoptosis. Recently, a novel regulatory single nucleotide polymorphism (-938C>A) in the inhibitory P2 BCL2 promoter was described. In this study we investigated its potential association with survival in epithelial ovarian cancer. EXPERIMENTAL DESIGN: Patients (n=110) with primary epithelial ovarian cancer were retrospectively genotyped by pyrosequencing....

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Share to BCL2 gene
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multivariate Analysis

Share to Ovarian Neoplasms

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins c-bcl-2

Source

Identifiers

PMID: 20082279
DOI: 10.1177/172460080902400402

Genes

BCL2

Provenance

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Association of the AA genotype of the BCL2 (-938C>A) promoter polymorphism with better survival in ovarian cancer.PMID 20082279Read ↗

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