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Article

The -938A/A genotype of BCL2 gene is associated with esophageal cancer.

Medical oncology (Northwood, London, England) - 1 Dec 2012

Liu Zhigang, Sun Ruifang, Lü Weidong, Dang Chengxue, Song Yangrong, Wang Cheng, Zhang Xi, Han Le, Cheng Hao, Gao Wei, Liu Jia, Lei Guangyan

Abstract excerpt

Perturbations in the apoptotic genes have been implicated in human malignancies. The purpose of the present study was to investigate the polymorphisms of -938C/A, Thr43Ala in anti-apoptotic B-cell lymphoma 2 gene (BCL2) and -248G/A in pro-apoptotic B-cell lymphoma 2-associated X protein gene (BAX) and to explore their role in influencing the susceptibility for development of esophageal cancer. A total of 205...

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Source

Identifiers

PMID: 22187149
DOI: 10.1007/s12032-011-0135-2

Genes

BCL2
BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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