Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BCL-2 (-938C > A) polymorphism is associated with breast cancer susceptibility.

BMC medical genetics - 1 Apr 2011

Zhang Ning, Li Xiaoyan, Tao Kai, Jiang Liyu, Ma Tingting, Yan Shi, Yuan Cunzhong, Moran Meena S, Liang Faming, Haffty Bruce G, Yang Qifeng

Abstract excerpt

BACKGROUND: BCL-2 (B-cell leukemia/lymphoma 2) gene has been demonstrated to be associated with breast cancer development and a single nucleotide polymorphism (SNP; -938C > A) has been identified recently. To investigate whether this polymorphism functions as a modifier of breast cancer development, we analyzed the distribution of genotype frequency, as well as the association of genotype with clinicopathological...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine
Share to Blotting, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cysteine

Share to Genes, bcl-2

Share to Logistic Models

Share to Lymphatic Metastasis

Share to Proto-Oncogene Proteins c-bcl-2

Share to Risk Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 21457555
DOI: 10.1186/1471-2350-12-48
PMCID: PMC3078853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BCL-2 (-938C > A) polymorphism is associated with breast cancer susceptibility.PMID 21457555Read ↗

Influence of BCL2-938 C>A promoter polymorphism and BCL2 gene expression on the progression of breast cancer.Semantic proximity Read ↗

Role of Bcl-2 -938 C>A polymorphism in susceptibility and prognosis of cancer: a meta-analysis.Semantic proximity Read ↗

The AA genotype of the regulatory BCL2 promoter polymorphism ( 938C>A) is associated with a favorable outcome in lymph node negative invasive breast cancer patients.Semantic proximity Read ↗

The -938A/A genotype of BCL2 gene is associated with esophageal cancer.Semantic proximity Read ↗

The bcl2 -938CC genotype has poor prognosis and lower survival in renal cancer.Semantic proximity Read ↗

Association of the AA genotype of the BCL2 (-938C>A) promoter polymorphism with better survival in ovarian cancer.Semantic proximity Read ↗

Association of a novel regulatory polymorphism (-938C>A) in the BCL2 gene promoter with disease progression and survival in chronic lymphocytic leukemia.Semantic proximity Read ↗

2q35-rs13387042 variant and the risk of breast cancer: a case-control study.Semantic proximity Read ↗

Association of genetic markers in the BCL-2 family of apoptosis-related genes with endometrial cancer risk in a Chinese population.Semantic proximity Read ↗

Associations of BCL2 CA-Repeat Polymorphism and Breast Cancer Susceptibility in Isfahan Province of Iran.Semantic proximity Read ↗

Coffee Intake Interacted with the Bcl-2 rs1944420, rs7236090, and rs2849382 Haplotype to Influence Breast Cancer Risk in Middle-Aged Women.Semantic proximity Read ↗

Evaluation of polymorphic variants in apoptotic genes (Bcl-2 / Bax) and their roles in the development of myeloproliferative disorders (hematological malignancies) a case-controlled study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.