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Article

Association of the CC genotype of the regulatory BCL2 promoter polymorphism (-938C>A) with better 2-year survival in patients with glioblastoma multiforme.

Journal of neurosurgery - 1 Jun 2011

El Hindy Nicolai, Bachmann Hagen S, Lambertz Nicole, Adamzik Michael, Nückel Holger, Worm Karl, Zhu Yuan, Sure Ulrich, Siffert Winfried, Sandalcioglu I Erol

Abstract excerpt

OBJECT: Bcl-2 plays a key role in the downregulation of apoptosis and proliferation and leads to increased chemoresistance in glioblastoma multiforme (GBM). The authors investigated the role of a common regulatory single-nucleotide polymorphism (-938C>A), which is located in the inhibitory P2 pro...

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Source

Identifiers

PMID: 21250804
DOI: 10.3171/2010.12.JNS10478

Genes

BCL2
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21250804-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association of the CC genotype of the regulatory BCL2 promoter polymorphism (-938C>A) with better 2-year survival in patients with glioblastoma multiforme.PMID 21250804Read ↗

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